Some of Drug interaction

DRUG INTERACTIONS:

 *Aluminium Hydroxide Gel + Pseudoephedrine = Decrease effect of that drug due to increases pH of gastric fluid

*Ciprofloxacin + Theophyline = Increases plasma level of Theophyline

* Aminoglycoside + beta-Lactam antibiotics= Synergestic  effect  but  if given  in  same syring   it‘s   become   inactive   due   to complex formation

* Cortisone + Ampicillin= Antagonist

*Erythromycin /Clarithromycin/ Telrithromycin + Carmazepam/ Phenytoin = Increases  level of    Carbamazapine  and Phenytoin

 *Methotrexate + Sulfamethoxazole = Displace from binding site and increases free plasma concentration of drug

*Amphotericin B + Flucytosine = Synergestic effect

* Ketoconazole + Amphotericin B = Antagonized   effect   due   to   decreases ergosterol level

*Azoles ( including All) + Terbinafine = Contraindicated

* Posconazole + Ergot alkaloid = Contraindicate

*Cimetidine + Terbinafine= increases plasma concentration of Terbinafine

* Gresiofulvin + Alcohol = Potentiate toxicity of alcohol

* Miconazole+ Warfarin = inhibit metabolism of warfarin

*MAO inhibitors + Pethidine = Hyperpyrexia

*TCA + SSRIs TCA =  toxicity